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Main Teachers Musralina Lyazzat Zenurainovna

Musralina Lyazzat Zenurainovna

Associate professor
The Department of «Biochemical engineering»

PhD

email: musralinal@gmail.com


Professional experience

More than 20 years of experience in molecular biology, paleogenetics, criminology and teaching. Participant of international projects and internships in Germany, USA, Canada and Singapore. He is the author of 11 articles and one book chapter indexed in Scopus (323). Competencies: ancient DNA, bioinformatics, Y-chromosome and mitochondrial analysis, next-generation sequencing, coordination of laboratory and scientific projects. From 2025 to the present, Associate Professor of the Department of Biochemical and Engineering, MЕTU.

Education

1999 - 2004 Al-Farabi Kazakh National University. Medical and Biological Sciences.

2015 - 2017 Al-Farabi Kazakh National University. Master of Science Degree.

2019 - 2023 Al-Farabi Kazakh National University. PhD, Биотехнология .

Scientific interests

Genetic Relationship Among the Kazakh People Based on Y-STR Markers Reveals Evidence of Genetic Variation Among Tribes and Zhuz



Publications

  1. Yeh, K. B., Parekh, F. K., Musralina, L., Sansyzbai, A., Tabynov, K., Shapieva, Z., Richards, A. L., & Hay, J. A. (2019). Case history in cooperative biological research: Compendium of studies and program analyses in Kazakhstan. Tropical Medicine and Infectious Disease, 4(4), 136. https://doi.org/10.3390/tropicalmed4040136
  2. Yegemberdiyeva, R., Shapiyeva, Z., Dmitrovskiy, A., Maykanov, N., Musralina, L., & Yeraliyeva, A. (2019). West Nile fever: Clinical and epidemiological manifestations. Vestnik KazNMU, 2, 93. https://cyberleninka.ru/article/n/lihoradka-zapadnogo-nila-kliniko-epidemiologicheskie-proyavleniya
  3. Tukhanova, N., Shin, A., Abdiyeva, K., Turebekov, N., Yeraliyeva, L., Yegemberdiyeva, R., Shapiyeva, Z., Froeschl, G., Hoelscher, M., Wagner, E., Rösel, K., Zhalmagambetova, A., Musralina, L., Frey, S., & Essbauer, S. (2020). Serological investigation of orthohantaviruses in patients with fever of unknown origin in Kazakhstan. Zoonoses and Public Health, 67(3), 271–279. https://doi.org/10.1111/zph.12683
  4. Djansugurova, L. B., Musralina, L. Z., Khussainova, E. M., Bekmanov, B. O., Samashev, Z. S., Gnecchi-Ruscone, G. A., & Krause, J. (2020). Paleogenetic analysis of human remains representing the Hunno-Xianbei layer of Berel in the Kazakh Altai. World of the Great Altai, 6(2), 949–958. https://www.vku.edu.kz/sites/default/files/files/nauka
  5. Gnecchi-Ruscone, G. A., Khussainova, E., Kahbatkyzy, N., Musralina, L., Spyrou, M. A., Bianco, R. A., ... Krause, J. (2021). Ancient genomic time transect from the Central Asian Steppe unravels the history of the Scythians. Science Advances, 7(13), eabe4414. https://doi.org/10.1126/sciadv.abe4414
  6. Musralina, L. Z., Khussainova, E. M., Altynova, N. K., Zhanyazov, Zh. A., Nurzhibek, K., Samashev, Z. S., Bekmanov, B. O., & Djansugurova, L. B. (2021). Paleogenetic analysis of ancient pathogens in human remains from the Berel region. Problems of Evolution of Open Systems, 2(23), 117–126. https://peos.kaznu.kz
  7. Turebekov, N., Abdiyeva, K., Yegemberdiyeva, R., Kuznetsov, A., Dmitrovskiy, A., Yeraliyeva, L., Shapiyeva, Z., ... Musralina, L., ... Essbauer, S. (2021). Rickettsia spp. antibodies in hospitalized patients with undifferentiated febrile illness in the southern region of Kazakhstan. American Journal of Tropical Medicine and Hygiene, 104(6), 2000–2008. https://doi.org/10.4269/ajtmh.20-0388
  8. Kocher, A., Papac, L., Barquera, R., Key, F. M., Spyrou, M. A., Hübler, R., ... Musralina, L., ... Krause, J., Kühnert, D. (2021). Ten millennia of hepatitis B virus evolution. Science, 374(6564), 182–188. https://doi.org/10.1126/science.abi5658
  9. Perfilyeva, A., Bespalova, K., Perfilyeva, Y., Musralina, L., Bekmanov, B., & Djansugurova, L. (2022). Integrative functional genomic analysis in multiplex autism families from Kazakhstan. Disease Markers, 2022, 1509994. https://doi.org/10.1155/2022/1509994
  10. Khussainova, E., Kisselev, I., Iksan, O., Musralina, L., Good, S. V., & Djansugurova, L. (2022). Genetic relationship among the Kazakh people based on Y-STR markers reveals evidence of genetic variation among tribes and zhuz. Frontiers in Genetics, 12, 801295. https://doi.org/10.3389/fgene.2021.801295
  11. Musralina, L. Z., Djansugurova, L. B., & Krause, J. (2022). Features of the study of ancient pathogens. Problems of Evolution of Open Systems, 22(1), 83–89. https://peos.kaznu.kz/index.php/peos/article/view/259
  12. Andrades Valtueña, A., Neumann, G. U., Spyrou, M. A., Musralina, L., Aron, F., Beisenov, A., ... Herbig, A. (2022). Stone Age Yersinia pestis genomes shed light on the early evolution, diversity, and ecology of plague. Proceedings of the National Academy of Sciences, 119(17), e2116722119. https://doi.org/10.1073/pnas.2116722119
  13. Spyrou, M. A., Musralina, L., Gnecchi Ruscone, G., Kocher, A., Borbone, P.-G., Khartanovich, V. I., ... Krause, J. (2022). The source of the Black Death uncovered from a 14th-century plague epidemic in Central Asia. Nature, 606(7915), 718–724. https://doi.org/10.1038/s41586-022-04800-3
  14. Shin, A., Tukhanova, N., Ndenkeh, J., Shapiyeva, R., Yegemberdiyeva, L., Yeraliyeva, T., Nurmakhanov, G., Froeschl, M., Hoelscher, L., Musralina, L., ... Essbauer, S. (2022). Tick-borne encephalitis virus and West Nile fever virus as causes of serous meningitis of unknown origin in Kazakhstan. Zoonoses and Public Health, 69(5), 514–525. https://doi.org/10.1111/zph.12941
  15. Musralina, L. Z., Khussainova, E. M., & Djansugurova, L. B. (2023). Genomic insights into ancient pathogens in Central Asia. Journal of Human Genetics, 68(4), 350–362. https://doi.org/10.1016/B978-0-323-99886-4.00002-8
  16. Altynova, N.K., Tokmurzina, S.S., Kassymbekova, A.M., Kereyev T.N., Musralina L.Z., Lebedeva, L.P., Djansugurova, L.B. (2024). Genetic markers of sports performance, interpretation of individual genotypes in the athlete’s genetic passport. International Journal of Biology and Chemistry, 17(2), 53–73. https://doi.org/10.26577/IJBCh2024v17.i2.6
Disciplines taught


Biotechnology of microorganisms

The purpose of the discipline is to familiarize students with the principles and features of microbiological processes used in biotechnology. As a result of the training, the student will comply with the requirements imposed on raw materials and microorganisms by producers, apply methods of cultivation of microorganisms, methods of isolation and purification of target products by specific industrial productions based on microbiological synthesis and transformation, conduct experiments using methods of cultivation of microorganisms.

Genetic Engineering

The purpose of the discipline is an in-depth study of the theoretical foundations of the design, cloning and expression of genetic material in bacterial and eukaryotic cells, as well as the creation of organisms with a new genetic program. As a result of the training, the student will be able to explain the practical significance of genetic engineering, describe the main directions of growing living cells, explain antigens and antibodies, and choose the designs of a recombinant DNA molecule.

Timetable of classes

Opening lessons